Daily Trends Now
Daily Trends Now

New Human Organ Holds a 5th of Body's Fluid

New Human Organ Holds a 5th of Body's Fluid

Called the interstitium, it consists of a series of fluid-filled, shock-absorbing compartments that shield body tissues. "For a body part to officially become an organ, a consensus would need to develop around the idea as more researchers study it", study author Dr. Neil Theise, a professor of pathology at New York University Langone School of Medicine, told Live Science.

Scientists report on their identification of a previously undetected, but widespread, structural feature in the human body that could play a key role in how tissues and organs function, and also impact on disease mechanisms and spread.

The press release states: "Importantly, the finding that this layer is a highway of moving fluid may explain why cancer that invades it becomes much more likely to spread".

To start to understand the function of the new organ the team designed a new method of tissue examination that involves the freezing of biopsy tissue, which helps preserve the anatomy of the organ.

Schematic of the fluid-filled space supported by a network of collagen bundles lined on one side with cells. For instance, scientists always knew that 20 percent of body fluids was missing in a total tally, in between blood, lymph, serum and other bodily fluids.

When slides were examined that's what it looked like, because to make a slide the fluid is drained away as part of the process.

Co-authors of the study David Carr-Locke and Petros Constantinos Benias have first encountered interstitium in 2015 while they investigate a bile duct from a cancer patient. Once the team recognized this new space in images of bile ducts, they quickly recognized it throughout the body, wherever tissues moved or where it was compressed by force.

The fluid-filled tissue is also though to act as a shock absorber for the body. Upon further scrutiny, they determined that the lattice is composed of collagen bundles that support fluid-filled spaces and are lined irregularly with flattened cells that produce two markers, one endothelial and one mesenchymal.

In his opinion, the interstitium acts as a source of lymph, the fluid vital to the functioning of immune cells and which carries infection-fighting white blood cells.

"This has both", he said of the interstitium, per CNN.

"This discovery will open up new research pathways for inflammation and cancer progression".

The new organ contains strong (collagen) and flexible (elastin) connective tissue proteins.

Called a "probe-based confocal laser endomicroscopy", or pCLE, it allows a microscopic view of living tissue. It has been identified in connective tissues, including those just below the surface of the skin.

For their latest studies, the team used a freezing technique to prepare surgically obtained tissue specimens from cancer patients in such a way that the interstitial compartments weren't disrupted.

The organ's true objective was finally discovered during a routine endoscopy looking at a patient's bile duct.

This fluid layer that surrounds most organs may explain why cancer spreads so easily. Researchers said interstitium could significantly advance the understanding of cancer and many other diseases.


editors' picks

March 29, 2018
Trump attorney discussed pardons with Flynn, Manafort lawyers
The White House and Trump's lawyers have regularly argued that the president is not considering pardons. Manafort, a former Trump campaign chairman, has pleaded not guilty .

March 28, 2018
Over 600 eggs anonymously donated to Easter Egg Appeal
At this time, we just do not feel that the construction areas would be safe for the children as they hunt for all 30,000 eggs . The Jaycees remind participants to bring their own baskets. "We wanted to serve the community", John Vanderpool said.

March 28, 2018
Israel detains armed Palestinians who breached Gaza border
The machinery was damaged but did not catch fire, and the attackers fled back into Gaza, she said. The Israeli army was checking reports of the firings and a spokesman declined immediate comment.

March 26, 2018
Sergio Garcia rallies on back nine to advance at Match Play
A win in the Round of 16 will boost the Englishman into the top 50 in the world and save him a spot at the Masters in two weeks. The other semifinal will pit Alex Noren against Kevin Kisner.

March 25, 2018
George Clooney, Paul McCartney and more celebrities join March for Our Lives
McCartney was referring to John Lennon , who was shot to death in the archway of his residence in 1980. Each wore t-shirts that read: "We Can End Gun Violence".

March 24, 2018
Loyola-Chicago vs. Nevada
Caleb Martin led Nevada's team in scoring with 21 points, while shooting 44.4% from the field (making 8 of 18 attempts). The narrow margin-wins for slight upsets in the Sweet 16 aren't the only similarities for K-State and Loyola-Chicago.

March 22, 2018
Gonzaga vs. Florida State - 3/22/18 College Basketball Pick, Odds, and Prediction
"We were much better than Xavier in the last two and a half minutes of the game", Florida State Coach Leonard Hamilton said. Because Florida State doesn't win this game without PJ Savoy - another of our favorites - doesn't do his thing.

March 22, 2018
Avengers: Infinity War Advance Ticket Sales Dwarf Black Panther
Those are moments Marvel fans have been wanting to see on the big screen for years, if not decades, and they're finally happening. The co-director added that Thor will have a lot of screen time in " Infinity War ".

March 21, 2018
Judge rules 'Apprentice' contestant's lawsuit against Trump may proceed
A much-anticipated interview with Daniels is scheduled to air Sunday (Monday NZT) on CBS's "60 Minutes". Jones , a stay for the duration of the Trump presidency must be denied ", the opinion states .

March 20, 2018
Tony Award Winner Cynthia Nixon Announces Candidacy for Governor of NY
Nixon enters a Democratic field that also includes Cuomo and former state senator Terry Gipson, of Rhinebeck, N.Y. She married her wife Christine Marinoni in 2012 after dating for eight years and has one child with her.